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All-<i>trans</i> Retinoic Acid Inhibits Hepatitis B Virus Replication by Downregulating HBx Levels via Siah-1-Mediated Proteasomal Degradation

All-<i>trans</i> retinoic acid (ATRA), the most biologically active metabolite of vitamin A, is known to abolish the potential of HBx to downregulate the levels of p14, p16, and p21 and to stimulate cell growth during hepatitis B virus (HBV) infection, contributing to its chemopreventive and therape...

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Principais autores: Jiwoo Han, Kyung Lib Jang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-06-01
Colecção:Viruses
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Acesso em linha:https://www.mdpi.com/1999-4915/15/7/1456
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