Molecular determination of antifolate resistance associated point mutations in Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthetase (dhps) genes among the field samples in Arunachal Pradesh

Background & objectives: Antimalarial resistance in P. falciparum malaria parasite creates a serious obstacle in malaria control programme. Keeping this in mind, in the present study antifolate resistance associated point mutations in P. falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroat...

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Detalhes bibliográficos

Principais autores:	Jitendra Sharma, S A Khan, Prafulla Dutta, Jagadish Mahanta
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2015-01-01
coleção:	Journal of Vector Borne Diseases
Assuntos:	Arunachal Pradesh; dhfr-dhps; haplotypes; locus; mutation; P. falciparum; sulphadoxine-pyrimethamine
Acesso em linha:	http://www.mrcindia.orgjournal/article.asp?issn=0972-9062;year=2015;volume=52;issue=2;spage=116;epage=121;aulast=Sharma
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