Insulin and insulin-like growth factor-I receptors in astrocytes exert different effects on behavior and Alzheimer´s-like pathology [version 3; peer review: 2 approved]

Background: Pleiotropic actions of insulin and insulin-like growth factor I (IGF-I) in the brain are context- and cell-dependent, but whether this holds for their receptors (insulin receptor (IR) and IGF-I receptor (IGF-IR), respectively), is less clear. Methods: We compared mice lacking IR or IGF-I...

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Hauptverfasser:	Raquel Herrero-Labrador, Jansen Fernandes, Ana M. Fernandez, Laura Martinez-Rachadell, Ignacio Torres Aleman, Jonathan Zegarra-Valdivia
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	F1000 Research Ltd 2022-12-01
Schriftenreihe:	F1000Research
Schlagworte:	Astrocytes Alzheimer`s disease Insulin Insulin-like growth factor I Glial cells. eng
Online-Zugang:	https://f1000research.com/articles/11-663/v3
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