Research progress on immune mechanism and control strategy of dsRNA impurities in mRNA vaccine
Introduction Double-stranded RNA (dsRNA) is a key impurity of mRNA vaccines prepared by in vitro transcription (IVT) and is primarily transcribed by T7 RNA polymerase. It can trigger innate immunity and induce a series of side effects that may influence the safety of mRNA vaccines.Areas covered This...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis Group
2025-12-01
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| Serie: | Expert Review of Vaccines |
| Soggetti: | |
| Accesso online: | https://www.tandfonline.com/doi/10.1080/14760584.2025.2510335 |
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