Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization

Introduction: Hydrogen sulfide (H2S) was revealed to inhibit aortic valve calcification and inflammation was implicated in the pathogenesis of calcific aortic valve disease (CAVD). Objectives: We investigate whether H2S inhibits mineralization via abolishing inflammation. Methods and results: Expres...

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Автори:	Katalin Éva Sikura, Zsolt Combi, László Potor, Tamás Szerafin, Zoltán Hendrik, Gábor Méhes, Péter Gergely, Matthew Whiteman, Lívia Beke, Ibolya Fürtös, György Balla, József Balla
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2021-01-01
Серія:	Journal of Advanced Research
Предмети:	H2S AP72 Aortic valve Inflammation CAVD Apolipoprotein E knockout mice
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2090123220301648
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Hydrogen sulfide inhibits aortic valve calcification in heart via regulating RUNX2 by NF-κB, a link between inflammation and mineralization

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