Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA Nephropathy

IgA nephropathy (IgAN) is the dominant type of primary glomerulonephritis worldwide. However, IgAN rarely affects African Blacks and is uncommon in African Americans. Polymeric IgA1 with galactose-deficient hinge-region glycans is recognized as auto-antigen by glycan-specific antibodies, leading to...

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Hlavní autoři:	Katerina Zachova, Petr Kosztyu, Josef Zadrazil, Karel Matousovic, Karel Vondrak, Petr Hubacek, Bruce A. Julian, Zina Moldoveanu, Zdenek Novak, Klara Kostovcikova, Milan Raska, Jiri Mestecky
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-02-01
Edice:	Frontiers in Immunology
Témata:	IgA EBV-Epstein-Barr virus racial distribution IgA nephropathy mucosal immunology
On-line přístup:	https://www.frontiersin.org/article/10.3389/fimmu.2020.00267/full
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