Functionalized silk spheres selectively and effectively deliver a cytotoxic drug to targeted cancer cells in vivo

Abstract Background Chemotherapy is often a first-line therapeutic approach for the treatment of a wide variety of cancers. Targeted drug delivery systems (DDSs) can potentially resolve the problem of chemotherapeutic drug off-targeting effects. Herein, we examined in vivo models to determine the ef...

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Hauptverfasser:	Anna Florczak, Tomasz Deptuch, Anna Lewandowska, Karolina Penderecka, Elzbieta Kramer, Andrzej Marszalek, Andrzej Mackiewicz, Hanna Dams-Kozlowska
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2020-12-01
Schriftenreihe:	Journal of Nanobiotechnology
Schlagworte:	Silk Particles Functionalization Bioengineering Targeted drug delivery Cancer
Online-Zugang:	https://doi.org/10.1186/s12951-020-00734-y
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