Role of type I interferons in inflammasome activation, cell death and disease during microbial infection
Interferons were discovered over a half-century ago as antiviral factors. The role of type I interferons (IFNs) has been studied in the pathogenesis of both acute and chronic microbial infections. Deregulated type I IFN production results in a damaging cascade of cell death, inflammation and immunol...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2013-11-01
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| Collection: | Frontiers in Cellular and Infection Microbiology |
| Sujets: | |
| Accès en ligne: | http://journal.frontiersin.org/Journal/10.3389/fcimb.2013.00077/full |
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