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Quercetin Induces Apoptosis in HepG2 Cells <i>via</i> Directly Interacting with YY1 to Disrupt YY1-p53 Interaction

Quercetin is a flavonol found in edible plants and possesses a significant anticancer activity. This study explored the mechanism by which quercetin prevented liver cancer <i>via</i> inducing apoptosis in HepG2 cells. Quercetin induced cell proliferation and apoptosis through inhibiting YY1 and faci...

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Principais autores: Hui Guan, Wenyuan Zhang, Hui Liu, Yang Jiang, Feng Li, Maoyu Wu, Geoffrey I. N. Waterhouse, Dongxiao Sun-Waterhouse, Dapeng Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-02-01
coleção:Metabolites
Assuntos:
quercetin-YY1 interaction
anticancer
apoptosis
YY1-p53 binding
binding competition
Acesso em linha:https://www.mdpi.com/2218-1989/13/2/229
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