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Inhibiting glycolysis facilitated checkpoint blockade therapy for triple-negative breast cancer

Abstract Cancer cells are characterized by their altered energy metabolism. A hallmark of cancer metabolism is aerobic glycolysis, also called the Warburg effect. Hexokinase 2 (HK2), a crucial glycolytic enzyme converting glucose to glucose-6-phosphate, has been identified as a central player in the...

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Hlavní autoři: Chong Li, Yu Tang, Ruizhi Zhang, Liang Shi, Jianying Chen, Peng Zhang, Ning Zhang, Wei Li
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer 2025-04-01
Edice:Discover Oncology
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On-line přístup:https://doi.org/10.1007/s12672-025-02320-w
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