Modeling and Optimization of the Culture Medium for Efficient 4′-N-Demethyl-Vicenistatin Production by <i>Streptomyces parvus</i> Using Response Surface Methodology and Artificial-Neural-Network-Genetic-Algorithm

4′-N-demethyl-vicenistatin is a vicenistatin analogue that has better antitumor activity with promising applications in the pharmaceuticals industry. The harnessing of the complete potential of this compound necessitates a systematic optimization of the culture medium to enable the cost-effective pr...

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Autors principals:	Zhixin Yu, Hongxin Fu, Jufang Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2024-03-01
Col·lecció:	Fermentation
Matèries:	culture medium optimization response surface methodology 4′-N-demethyl-vicenistatin <i>Streptomyces parvus</i> artificial-neural-network-genetic-algorithm
Accés en línia:	https://www.mdpi.com/2311-5637/10/3/154
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