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Cryogenic microcarrier-assisted stem cell storage (Cryo-MASCS): a preservation method enabling scalable culture of human mesenchymal stem cells

Abstract Microcarrier (µC) suspension systems enable closed, high-density manufacturing of human mesenchymal stem cells (MSCs), but current workflows remain labor-intensive because they require post-thaw cryoprotectant removal and static culture steps to allow cell attachment. To address these bottl...

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Principais autores: Carolina Rivera-Crespo, Leonel Velez-Román, Miosotis Acevedo-Esquilin, Heath J. Mills, Olivia Gámez Holzhaus, Maribella Domenech-García
Format: Artigo
Jezik:Inglês
Izdano: BMC 2025-12-01
Serija:Stem Cell Research & Therapy
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Online dostop:https://doi.org/10.1186/s13287-025-04871-9
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