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Coagulation modifiers targeting SARS-CoV-2 main protease Mpro for COVID-19 treatment: an in silico approach

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection depends on viral polyprotein processing, catalysed by the main proteinase (Mpro). The solution of the SARS-CoV-2 Mpro structure allowed the investigation of potential inhibitors. This work aims to provide first evidences of the a...

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Bibliografiske detaljer
Principais autores: Ísis Venturi Biembengut, Tatiana de Arruda Campos Brasil de Souza
Format: Artigo
Sprog:Inglês
Udgivet: Fundação Oswaldo Cruz (FIOCRUZ)
Serier:Memorias do Instituto Oswaldo Cruz
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Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762020000100407&lng=en&tlng=en
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