Carbon Dioxide-Derived Biodegradable and Cationic Polycarbonates as a New siRNA Carrier for Gene Therapy in Pancreatic Cancer

Pancreatic cancer is an aggressive malignancy associated with poor prognosis and a high tendency in developing infiltration and metastasis. K-ras mutation is a major genetic disorder in pancreatic cancer patient. RNAi-based therapies can be employed for combating pancreatic cancer by silencing K-ras...

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Detalhes bibliográficos

Principais autores:	Xinmeng Zhang, Zheng-Ian Lin, Jingyu Yang, Guan-Lin Liu, Zulu Hu, Haoqiang Huang, Xiang Li, Qiqi Liu, Mingze Ma, Zhourui Xu, Gaixia Xu, Ken-Tye Yong, Wei-Chung Tsai, Tzu-Hsien Tsai, Bao-Tsan Ko, Chih-Kuang Chen, Chengbin Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-09-01
Colecção:	Nanomaterials
Assuntos:	cationic polycarbonates biodegradable pancreatic cancer siRNA delivery K-ras
Acesso em linha:	https://www.mdpi.com/2079-4991/11/9/2312
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