The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation

Abstract Background Disruption of the extracellular matrix at the blood–brain barrier (BBB) underpins neuroinflammation in multiple sclerosis (MS). The degradation of extracellular matrix components, such as heparan sulfate (HS) proteoglycans, can be prevented by treatment with HS-mimetics through t...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Tessa Peck, Connor Davis, Georgia Lenihan-Geels, Maddie Griffiths, Sam Spijkers-Shaw, Olga V. Zubkova, Anne Camille La Flamme
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2023-11-01
Цуврал:	Journal of Neuroinflammation
Нөхцлүүд:	EAE MS HS HSPG Neuroinflammation Migration
Онлайн хандалт:	https://doi.org/10.1186/s12974-023-02925-4
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!