Raman spectroscopy and group and basis-restricted non negative matrix factorisation identifies radiation induced metabolic changes in human cancer cells

Abstract This work combines single cell Raman spectroscopy (RS) with group and basis restricted non-negative matrix factorisation (GBR-NMF) to identify individual biochemical changes associated with radiation exposure in three human cancer cell lines. The cell lines analysed were derived from lung (...

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Hlavní autoři:	Kirsty Milligan, Xinchen Deng, Phillip Shreeves, Ramie Ali-Adeeb, Quinn Matthews, Alexandre Brolo, Julian J. Lum, Jeffrey L. Andrews, Andrew Jirasek
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2021-02-01
Edice:	Scientific Reports
On-line přístup:	https://doi.org/10.1038/s41598-021-83343-5
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