Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model

Mitogen- and Stress-Activated Kinase 1 (MSK1) is a nuclear kinase, taking part in the activation pathway of the pro-inflammatory transcription factor NF-kB and is demonstrating a therapeutic target potential in inflammatory diseases such as asthma, psoriasis and atherosclerosis. To date, few MSK1 in...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Maud Bollenbach, Simona Nemska, Patrick Wagner, Guillaume Camelin, François Daubeuf, Adeline Obrecht, Pascal Villa, Didier Rognan, Frédéric Bihel, Jean-Jacques Bourguignon, Martine Schmitt, Nelly Frossard
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2021-01-01
Reeks:	Molecules
Onderwerpen:	Pyridine-2-yl guanidine MSK1 kinase inhibitors inflammation asthma
Online toegang:	https://www.mdpi.com/1420-3049/26/2/391
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!