PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

ABSTRACT Gastric cancer (GC) remains an aggressive malignancy with limited effective therapeutic options. Integrated single‐cell and bulk transcriptomic analyses identify protein disulfide isomerase A6 (PDIA6) as a tumor epithelial–enriched gene associated with advanced tumor‑ node‑metastasis (TNM)...

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Autori principali:	Zhen Tian, Yifan Cheng, Jiajie Zhou, Ruiqi Li, Shuai Zhao, Ben Li, Zijie Xu, Mengli Zi, Yayan Fu, Chenkai Zhang, Qiannan Sun, Shantanu Baral, Sen Wang, Daorong Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2026-08-01
Serie:	Advanced Science
Soggetti:	cancer‐associated fibroblasts gastric cancer lipid metabolism protein disulfide isomerase
Accesso online:	https://doi.org/10.1002/advs.75923
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