ENDOU-1-induced cytoplasmic HnRNPA3 recognizes m6A methylation on the upstream reading frame of human CHOP transcripts to achieve maximal CHOP translation

Abstract Translation of the coding sequence for human C/EBP homologous protein (CHOP) is highly regulated by its upstream open reading frame (uORF chop ). ENDOU-1 was shown to play positive roles in mediating CHOP translation through suppressing uORF chop -mediated translational inhibition (uORF cho...

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Autors principals:	Hung-Chieh Lee, Yi-Hsin Huang, Chi-Cheng Hsieh, Yi-Nan Ke, Huai-Jen Tsai
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer 2026-03-01
Col·lecció:	Cellular and Molecular Life Sciences
Matèries:	HnRNPA3 uORF m6A ENDOU-1 Translational control
Accés en línia:	https://doi.org/10.1007/s00018-026-06180-7
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