Pyrrolidine dithiocarbamate accelerates early recovery of intestinal microvascular oxygenation in a reversible model of hemorrhagic shock in rats

Abstract Background Improving intestinal tissue integrity appears to be crucial for maintaining global homeostasis in patients suffering from hemorrhagic shock. Since depletion of regional oxygen reserve might lead to cell death and tissue injury, the maintenance of regional tissue oxygenation appea...

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Autori principali:	Stefan Hof, Leandra Krüll, Jeanne Schmitt, Christopher Neumann, Carsten Marcus, Anne Kuebart, Anna Herminghaus, Borna Relja, Christian Vollmer, Inge Bauer, Olaf Picker, Richard Truse
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-11-01
Serie:	Journal of Translational Medicine
Soggetti:	PDTC Heme oxygenase-1 HO-1 µHbO2 Hemorrhagic shock Intestine
Accesso online:	https://doi.org/10.1186/s12967-025-07413-2
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