Sensing of protease activity as a triggering mechanism of Th2 cell immunity and allergic disease

CD4 T-helper cell type 2 (Th2) cells mediate host defense against extracellular parasites, like helminths. However, Th2 cells also play a pivotal role in the onset and progression of allergic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma, and food allergy. This happens w...

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Detalhes bibliográficos

Principais autores:	Audrey Meloun, Beatriz León
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-09-01
coleção:	Frontiers in Allergy
Assuntos:	protease allergens der p 1 protease-activated receptor 2 (PAR2) mas-related G-protein-coupled receptors (Mrgprs) nociceptor sensory neurons epithelial cells
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/falgy.2023.1265049/full
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