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Pharmacogenomic polygenic risk score for clopidogrel responsiveness among Caribbean Hispanics: A candidate gene approach

Abstract This multicenter clinical study was aimed at conducting a targeted pharmacogenomic association analysis of residual on‐clopidogrel platelet reactivity in 474 Caribbean Hispanic patients. Platelet reactivity was measured using the VerifyNow P2Y12 assay and clopidogrel resistance was defined...

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Principais autores: Jorge Duconge, Ednalise Santiago, Dagmar F. Hernandez‐Suarez, Mariangeli Moneró, Andrés López‐Reyes, Marines Rosario, Jessicca Y. Renta, Pablo González, Laura Ileana Fernández‐Morales, Luis Antonio Vélez‐Figueroa, Orlando Arce, Frances Marín‐Maldonado, Héctor Nuñez, Kyle Melin, Stuart A. Scott, Gualberto Ruaño
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2021-11-01
coleção:Clinical and Translational Science
Acesso em linha:https://doi.org/10.1111/cts.13124
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