Dynamic evolution of NK cells and immune remodeling mediated by CRS + HIPEC: prognostic mechanisms and therapeutic implications for malignant peritoneal mesothelioma

Abstract Background Malignant peritoneal mesothelioma (MPM) is a highly aggressive peritoneal malignancy with a significant recurrence rate following cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC). There is an urgent need to investigate novel therapeutic...

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Hlavní autoři:	Yi-Tong Liu, Qi-Di Zhao, Xin-Li Liang, Ru Ma, Yan-Dong Su, Rui Yang, Tian Wei, He-Liang Wu, Yu-Bin Fu, Yu-Run Cui, Yang Yu, Bing Li, Yan Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-11-01
Edice:	World Journal of Surgical Oncology
Témata:	Malignant peritoneal mesothelioma Natural killer cells Cytoreductive surgery Tumor microenvironment
On-line přístup:	https://doi.org/10.1186/s12957-025-04019-2
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