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Integrative multiomics evaluation reveals the importance of pseudouridine synthases in hepatocellular carcinoma

Background: The pseudouridine synthases (PUSs) have been reported to be associated with cancers. However, their involvement in hepatocellular carcinoma (HCC) has not been well documented. Here, we assess the roles of PUSs in HCC.Methods: RNA sequencing data of TCGA-LIHC and LIRI-JP were downloaded f...

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Hlavní autoři: Zhipeng Jin, Mengying Song, Jianping Wang, Wenjing Zhu, Dongxu Sun, Huayuan Liu, Guangjun Shi
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-11-01
Edice:Frontiers in Genetics
Témata:
pseudouridine synthase
HCC
biomarker
tumor microenvironment
multiomics data
On-line přístup:https://www.frontiersin.org/articles/10.3389/fgene.2022.944681/full
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