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Self-supervised classification of subcellular morphometric phenotypes reveals extracellular matrix-specific morphological responses

Abstract Cell morphology is profoundly influenced by cellular interactions with microenvironmental factors such as the extracellular matrix (ECM). Upon adhesion to specific ECM, various cell types are known to exhibit different but distinctive morphologies, suggesting that ECM-dependent cell morphol...

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Bibliografiske detaljer
Principais autores: Kin Sun Wong, Xueying Zhong, Christine Siok Lan Low, Pakorn Kanchanawong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2022-09-01
Serier:Scientific Reports
Online adgang:https://doi.org/10.1038/s41598-022-19472-2
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