RP-CAD for Lipid Quantification: Systematic Method Development and Intensified LNP Process Characterization

Lipid nanoparticles (LNPs) and their versatile nucleic acid payloads bear great potential as delivery systems. Despite their complex lipid composition, their quality is primarily judged by particle characteristics and nucleic acid encapsulation. In this study, we present a holistic reversed-phase (R...

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Bibliographic Details

Main Authors:	Nicole Beckert, Annabelle Dietrich, Jürgen Hubbuch
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2024-09-01
Series:	Pharmaceuticals
Subjects:	lipid nanoparticles charged aerosol detection power function value reversed-phase chromatography bioprocessing method validation
Online Access:	https://www.mdpi.com/1424-8247/17/9/1217
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