Endocortical Trabecularization in Acromegaly: The Cause for the Paradoxically Increased Vertebral Fracture Risk?

ABSTRACT Growth hormone (GH) is nonphysiologically increased in acromegaly, stimulating target tissues directly and indirectly via insulin‐like growth factor type 1 (IGF‐1). Despite GH having anabolic effects on bone growth and renewal, the risk of vertebral fractures is paradoxically increased in a...

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Bibliographic Details

Main Authors:	Ansgar Heck, Kristin Godang, Tove Lekva, Kjersti Norman Markussen, Sara De Vincentis, Thor Ueland, Jens Bollerslev
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2023-10-01
Series:	JBMR Plus
Subjects:	DXA hip structural analysis remodeling TBS trabecular separation
Online Access:	https://doi.org/10.1002/jbm4.10787
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