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Interpretable machine learning for predicting the response duration to Sintilimab plus chemotherapy in patients with advanced gastric or gastroesophageal junction cancer

BackgroundSintilimab plus chemotherapy has proven effective as a combination immunotherapy for patients with advanced gastric and gastroesophageal junction adenocarcinoma (GC/GEJC). A multi-center study conducted in China revealed a median progression-free survival (PFS) of 7.1 months. However, the...

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Principais autores: Dan-qi Wang, Wen-huan Xu, Xiao-wei Cheng, Lei Hua, Xiao-song Ge, Li Liu, Xiang Gao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Immunology
Fag:
Sintilimab
immunotherapy
progression-free survival
machine learning
interpretability
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1407632/full
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