Effect of Decorin and Aligned Collagen Fibril Topography on TGF-β1 Activation of Corneal Keratocytes

During corneal wound healing, transforming growth factor-beta 1 (TGF-β1) causes differentiation of quiescent keratocytes into myofibroblasts. Decorin has been investigated as a promising anti-fibrotic therapeutic for corneal healing due to its interaction with TGF-β1, collagen, and cell surface rece...

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Bibliografiske detaljer

Principais autores:	Nathaniel S. Tjahjono, Divya Subramanian, Tarik Z. Shihabeddin, Hudson D. Hicks, Victor D. Varner, W. Matthew Petroll, David W. Schmidtke
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2025-03-01
Serier:	Bioengineering
Fag:	decorin aligned collagen fibrils corneal keratocytes transforming growth factor-beta alpha-smooth muscle actin
Online adgang:	https://www.mdpi.com/2306-5354/12/3/259
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