Multifunctional roles of Brl1-Brr6 in nuclear envelope fusion during nuclear pore complex biogenesis

Abstract Brl1 and Brr6 are integral membrane proteins of the yeast nuclear envelope (NE) that transiently associate with nuclear pore complexes (NPCs). The exact roles of Brl1 and Brr6 during NPC assembly are unclear. Here, we demonstrate that Brr6 operates at both early and late stages of NPC assem...

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Detalles Bibliográficos

Autores principales:	Sayan Mondal, Annett Neuner, Azqa Ajmal Khan, Jlenia Vitale, Elmar Schiebel
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Springer Nature 2026-02-01
Colección:	The EMBO Journal
Materias:	Brl1 Brr6 Nuclear Pore Complex Nuclear Pore Complex Assembly Nuclear Envelope Fusion
Acceso en línea:	https://doi.org/10.1038/s44318-026-00718-y
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