Ex vivo propagation of synaptically-evoked cortical depolarizations in a mouse model of Alzheimer’s disease at 20 Hz, 40 Hz, or 83 Hz

Abstract Sensory stimulations at 40 Hz gamma (but not any other frequency), have shown promise in reversing Alzheimer’s disease (AD)-related pathologies. What distinguishes 40 Hz? We hypothesized that stimuli at 40 Hz might summate more efficiently (temporal summation) or propagate more efficiently...

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Hlavní autoři:	Aayushi A. Patel, Mei Hong Zhu, Riqiang Yan, Srdjan D. Antic
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-10-01
Edice:	Scientific Reports
Témata:	Alzheimer’s disease High gamma Excitatory postsynaptic potentials Cortical layer
On-line přístup:	https://doi.org/10.1038/s41598-024-74262-2
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