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Genome-wide profiling of transcribed enhancers during macrophage activation

Abstract Background Macrophages are sentinel cells essential for tissue homeostasis and host defence. Owing to their plasticity, macrophages acquire a range of functional phenotypes in response to microenvironmental stimuli, of which M(IFN-γ) and M(IL-4/IL-13) are well known for their opposing pro-...

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Principais autores: Elena Denisenko, Reto Guler, Musa M. Mhlanga, Harukazu Suzuki, Frank Brombacher, Sebastian Schmeier
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2017-10-01
Serier:Epigenetics & Chromatin
Fag:
Transcriptional enhancers
eRNA
Transcriptional regulation
Macrophage activation
Online adgang:http://link.springer.com/article/10.1186/s13072-017-0158-9
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