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Prominent mediatory role of gut microbiome in the effect of lifestyle on host metabolic phenotypes

Lifestyle factors influence both gut microbiome composition and host metabolism, yet their combined and mediating effects on host phenotypes remain poorly characterized in cardiometabolic populations. In 1,643 participants from the MetaCardis study, we developed a composite lifestyle score (QASD: di...

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Principais autores: Solia Adriouch, Eugeni Belda, Timothy D. Swartz, Sofia Forslund, Edi Prifti, Judith Aron-Wisnewsky, Rima Chakaroun, Trine Nielsen, Christine Poitou, Pierre Bel-Lassen, Christine Rouault, Tiphaine Le Roy, Petros Andrikopoulos, Kanta Chechi, Francesc Puig-Castellví, Inés Castro Dionicio, Philippe Froguel, Bridget Holmes, Rohia Alili, Fabrizio Andreelli, Hedi Soula, Joe-Elie Salem, Gwen Falony, Sara Vieira-Silva, Jeroen Raes, Peer Bork, Michael Stumvoll, Oluf Pedersen, S. Dusko Ehrlich, Marc-Emmanuel Dumas, Jean-Michel Oppert, Maria Carlota Dao, Jean-Daniel Zucker, Karine Clément
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2025-12-01
coleção:Gut Microbes
Assuntos:
Gut microbiome
nutrition
lifestyle
mediation
Acesso em linha:https://www.tandfonline.com/doi/10.1080/19490976.2025.2599565
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