CXCR5 guides migration and tumor eradication of anti-EGFR chimeric antigen receptor T cells
The efficacy of chimeric antigen receptor (CAR) T is still not optimal for solid tumors, partly due to the lack of T cell infiltration to the tumor site. One promising strategy is to guide T cells through tumor-specific chemokines, provided that the matching chemokine receptors are expressed on T ce...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2021-09-01
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| Serie: | Molecular Therapy: Oncolytics |
| Soggetti: | |
| Accesso online: | http://www.sciencedirect.com/science/article/pii/S2372770521001005 |
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