Responsive manganese-based nanoplatform amplifying cGAS-STING activation for immunotherapy

Abstract Background The activation of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway has attracted great attention for its ability to up-regulate innate immune response and thus enhance cancer immunotherapy. However,...

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Hlavní autoři:	Qingbin He, Runxiao Zheng, Junchi Ma, Luyang Zhao, Yafang Shi, Jianfeng Qiu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Association for the Advancement of Science (AAAS) 2023-04-01
Edice:	Biomaterials Research
Témata:	Tumor responsiveness cGAS-STING signaling pathway Immunotherapy Manganese ions Reactive oxygen species
On-line přístup:	https://doi.org/10.1186/s40824-023-00374-x
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