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Cancer cells transfer invasive properties through microRNAs contained in collagen tracks

Summary: Invasion is a prerequisite for metastasis formation. During tumor development, type I collagen overexpression increases tumor microenvironment stiffness, facilitating cancer cell dissemination. During breast cancer cell migration in 2D and 3D matrices, we observed membrane debris left behin...

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Principais autores: Lucile Rouyer, Léa Normand, Elodie Richard, Nathalie Allain, Julie Giraud, Sylvaine Di-Tommaso, Cyril Dourthe, Anne-Aurélie Raymond, Jean-William Dupuy, Kevin Moreau, Richard Iggo, Gaetan MacGrogan, Nathalie Dugot-Senant, Anthony Bouter, Sisareuth Tan, Alexandre Favereaux, Violaine Moreau, Reini F. Luco, Manon Ros, Frédéric Saltel
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2025-12-01
Serier:Cell Reports
Fag:
CP: Cancer
Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124725014974
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