FCGR3A and FCGR2A Genotypes Differentially Impact Allograft Rejection and Patients' Survival After Lung Transplant

Fc gamma receptors (FcγRs) play a major role in the regulation of humoral immune responses. Single-nucleotide polymorphisms (SNPs) of FCGR2A and FCGR3A can impact the expression level, IgG affinity and function of the CD32 and CD16 FcγRs in response to their engagement by the Fc fragment of IgG. The...

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Principais autores:	Pascale Paul, Pascal Pedini, Luc Lyonnet, Julie Di Cristofaro, Anderson Loundou, Mathieu Pelardy, Agnes Basire, Françoise Dignat-George, Jacques Chiaroni, Pascal Thomas, Martine Reynaud-Gaubert, Christophe Picard
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2019-06-01
סדרה:	Frontiers in Immunology
נושאים:	Fc-gamma receptors natural killer cells lung transplantation chronic lung allograft dysfunction HLA antibodies allograft rejection
גישה מקוונת:	https://www.frontiersin.org/article/10.3389/fimmu.2019.01208/full
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