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Vaccinia Virus Attenuation by Codon Deoptimization of the A24R Gene for Vaccine Development

ABSTRACT Poxviruses have large DNA genomes, and they are able to infect multiple vertebrate and invertebrate animals, including humans. Despite the eradication of smallpox, poxvirus infections still remain a significant public health concern. Vaccinia virus (VV) is the prototypic member in the poxvi...

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Autori principali: María M. Lorenzo, Aitor Nogales, Kevin Chiem, Rafael Blasco, Luis Martínez-Sobrido
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2022-06-01
Serie:Microbiology Spectrum
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Accesso online:https://journals.asm.org/doi/10.1128/spectrum.00272-22
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