A Robust FISH Assay to Detect FGFR2 Translocations in Intrahepatic Cholangiocarcinoma Patients

FGFR fusions retaining the FGFR kinase domain are active kinases that are either overexpressed or constitutively activated throughout diverse cancer types. The presence of FGFR translocations enhances tumor cell proliferation and contributes to significant sensitivity to FGFR kinase inhibitors. FGFR...

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Hlavní autoři:	Lei Zhang, Hao Zheng, Linyu Xu, Si You, Yuanyuan Shen, Yang Han, Steve Anderson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2023-06-01
Edice:	Diagnostics
Témata:	FGFR2 translocation intrahepatic cholangiocarcinoma break-apart FISH biallelic translocation
On-line přístup:	https://www.mdpi.com/2075-4418/13/12/2088
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