Host gene expression in the Nasopharynx can discriminate microbiologically confirmed viral and bacterial lower respiratory tract infection

Abstract Introduction: Distinguishing viral versus bacterial lower respiratory tract infection (LRTI) is challenging. We previously developed a rapid, host response-based test (Biomeme HR-B/V assay) using peripheral blood samples to identify viral versus bacterial infection. We assessed the perfor...

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Autori principali:	L. Gayani Tillekeratne, Nicholas O’Grady, Maria D. Iglesias-Ussel, Jack Anderson, Alana Brown, Armstrong Obale, Christina Nix, Champica K. Bodinayake, Ajith Nagahawatte, Robert Rolfe, E. Wilbur Woodhouse, Gaya B. Wijayaratne, Senali Weerasinghe, U.H.B.Y. Dilshan, Jayani Gamage, Ruvini Kurukulasooriya, Madureka Premamali, Himali S. Jayasinghearachchi, Bradly P. Nicholson, Emily R. Ko, Ephraim L. Tsalik, Micah T. McClain, Rachel A. Myers, Christopher W. Woods, Thomas W. Burke
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cambridge University Press 2025-01-01
Serie:	Journal of Clinical and Translational Science
Soggetti:	Lower respiratory tract infection host response antimicrobial stewardship nasopharynx rapid diagnostic
Accesso online:	https://www.cambridge.org/core/product/identifier/S205986612510191X/type/journal_article
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