Caspase-activation powers anti-Desmoglein 3-induced acantholysis in human epidermis

Abstract Pemphigus vulgaris (PV) is a life-threatening autoimmune blistering disease caused by circulating autoantibodies against desmoglein (Dsg) 1 and Dsg 3. Whether acantholysis in PV results exclusively from antibody binding to Dsgs or involves additional factors remains controversial. Given tha...

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Bibliographic Details

Main Authors:	Morna F. Schmidt, Maria A. Feoktistova, Diana Panayotova-Dimitrova, Eva Miriam Buhl, Peter Boor, Tim Ruhl, Jens Waschke, Ritva Tikkanen, Martin Röcken, Jens M. Baron, Amir S. Yazdi
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2026-02-01
Series:	Cell Death Discovery
Online Access:	https://doi.org/10.1038/s41420-026-02963-w
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