Aspidosperma nitidum reduces parasite load and modulates cytokines in BALB/c mice infected with Leishmania (Leishmania) amazonensis

The lack of vaccines shows the need for alternative leishmaniasis treatments. In vitro study previously demonstrated the leishmanicidal activity of A. nitidum extracts. This study describes for the first time, the antileishmanial activity of A. nitidum extracts in infected Balb/c mice and its immuno...

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Principais autores:	Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Antônio Rafael Quadros Gomes, Jorddy Neves Cruz, Juliana Correa-Barbosa, José Edson de Sousa Siqueira, Cristian Kallahan Silva Chagas, Andrey Moacir do Rosário Marinho, Liliane Almeida Carneiro, Márlia Regina Coelho-Ferreira, Sandro Percário, Maria Fâni Dolabela
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2024-10-01
Series:	Frontiers in Chemistry
Assuntos:	Aspidosperma nitidum Apocynaceae alkaloids Leishmania amazonensis Balb/c IFN-γ
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fchem.2024.1492770/full
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