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Design, synthesis, and evaluation of naphthalidinamide analogues as nonsteroidal mineralocorticoid receptor antagonists

Inappropriate overactivation of the mineralocorticoid receptor by the steroid hormones aldosterone or cortisol contributes to the development of cardiovascular diseases. The new mineralocorticoid receptor antagonist can directly block mineralocorticoid receptor overactivation, inhibit inflammation a...

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Principais autores: Mingguang Zhang, Yan Pang, Yurui Zhao, Sibei Chen, Cheng Guo
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publishing 2025-07-01
Serija:Journal of Chemical Research
Online dostop:https://doi.org/10.1177/17475198251351168
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