Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

Sister chromatid cohesion essential for mitotic chromosome segregation is thought to involve the co-entrapment of sister DNAs within cohesin rings. Although cohesin can load onto chromosomes throughout the cell cycle, it only builds cohesion during S phase. A key question is whether cohesion is gene...

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Hlavní autoři:	Madhusudhan Srinivasan, Marco Fumasoni, Naomi J Petela, Andrew Murray, Kim A Nasmyth
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	eLife Sciences Publications Ltd 2020-06-01
Edice:	eLife
Témata:	cohesin shister chromatid cohesion SMC replication replisome
On-line přístup:	https://elifesciences.org/articles/56611
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