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A trigger for opioid misuse: Chronic pain and stress dysregulate the mesolimbic pathway and kappa opioid system

Pain and stress are protective mechanisms essential in avoiding harmful or threatening stimuli and ensuring survival. Despite these beneficial roles, chronic exposure to either pain or stress can lead to maladaptive hormonal and neuronal modulations that can result in chronic pain and a wide spectru...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Nicolas Massaly, Jose A Moron, Ream Al-Hasani
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2016-11-01
Rangatū:Frontiers in Neuroscience
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00480/full
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