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Relationship between gene expression patterns from nasopharyngeal swabs and serum biomarkers in patients hospitalized with COVID-19, following treatment with the neutralizing monoclonal antibody bamlanivimab

Abstract Background A thorough understanding of a patient’s inflammatory response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is crucial to discerning the associated, underlying immunological processes and to the selection and implementation of treatment strategies. Def...

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Hlavní autoři: Jonathan T. Sims, Josh Poorbaugh, Ching-Yun Chang, Timothy R. Holzer, Lin Zhang, Sarah M. Engle, Stephanie Beasley, Thompson N. Doman, Lynn Naughton, Richard E. Higgs, Nicole Kallewaard, Robert J. Benschop
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2022-03-01
Edice:Journal of Translational Medicine
Témata:
Biomarkers
COVID-19
Gene expression
Bamlanivimab
Luminex
RNA-seq
On-line přístup:https://doi.org/10.1186/s12967-022-03345-3
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