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KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway

Abstract Background Bladder cancer (BCa) is a common malignancy characterized by high heterogeneity, yet the current treatment modalities are limited. The aim of the present investigation was to unravel the functional role of Karyopherin alpha 2 (KPNA2), a tumor facilitator identified in multiple ma...

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Библиографические подробности
Главные авторы: Fanchang Zeng, Liumei Luo, Daoyuan Li, Juncheng Guo, Min Guo
Формат: Artigo
Язык:Inglês
Опубликовано: BMC 2021-03-01
Серии:Journal of Translational Medicine
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Online-ссылка:https://doi.org/10.1186/s12967-021-02709-5
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