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MicroRNA-30b-5p inhibits autophagy in ovarian granulosa cells in polycystic ovary syndrome rats by targeting Atg5

Objective·To explore the expression of microRNA-30b-5p (miR-30b-5p) in polycystic ovary syndrome (PCOS) rats and the effect of miR-30b-5p overexpression on ovarian granulosa cell (GC) autophagy.Methods·Dehydroepiandrosterone (DHEA) was performed to establish a PCOS rat model, and real-time fluoresce...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: WANG Xuemin, WANG Yanan, NIU Aiqin, YE Ying, LI Fei
Format: Artigo
Sprache:Chinês
Veröffentlicht: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2023-01-01
Schriftenreihe:Shanghai Jiaotong Daxue xuebao. Yixue ban
Schlagworte:
polycystic ovary syndrome
microrna-30b-5p
autophagy
autophagy-associated protein 5 homologue(atg5)
proliferation
apoptosis
Online-Zugang:https://xuebao.shsmu.edu.cn/article/2023/1674-8115/1674-8115-2023-43-1-20.shtml
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