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Disproportionate adverse event signals of selumetinib in neurofibromatosis type I: insights from FAERS

BackgroundNeurofibromatosis type 1 (NF1) is a rare neurogenetic disorder with limited treatment options. Selumetinib, a MEK1/2 inhibitor, has emerged as a promising therapy for inoperable NF1-related plexiform neurofibromas.MethodsOur retrospective pharmacovigilance study utilized the FDA Adverse Ev...

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Váldodahkki: Lin Li
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Frontiers Media S.A. 2025-01-01
Ráidu:Frontiers in Pharmacology
Fáttát:
Liŋkkat:https://www.frontiersin.org/articles/10.3389/fphar.2024.1454418/full
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