Non-Invasive Measurement of Elasticity in Glioblastoma Multiforme Validates Decreased TMZ Sensitivity in Astrocyte Co-Culture

<italic>Goal:</italic> In this research, we investigated the changes in elasticity of in vitro glioblastoma multiforme (GBM) spheroids when treated with the gold standard chemotherapy for GBM, Temozolomide (TMZ). Additionally, we aimed to use this alternative biomarker to assess how modifying the tu...

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Autors principals:	Megan Mendieta, Maryam Hatami, Manmohan Singh, Sajedeh Saeidi Fard, Mohammad Dehshiri, Alexander Schill, Dmitry Nevozhay, Salavat Aglyamov, Bulent Ozpolat, Konstantin V. Sokolov, Yasemin M. Akay, Kirill V. Larin, Metin Akay
Format:	Artigo
Idioma:	Inglês
Publicat:	IEEE 2025-01-01
Col·lecció:	IEEE Open Journal of Engineering in Medicine and Biology
Matèries:	Brillouin GBM OCE spheroid stiffness
Accés en línia:	https://ieeexplore.ieee.org/document/10836794/
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